Shandong Pulisi Chemical provides comprehensive chemical raw material supply solutions for global enterprises, ensuring reliable quality control and optimized supply chain systems.
In modern personal care formulations, chelating agents play an indispensable role in maintaining product stability, transparency, and efficacy. While synthetic chelators such as EDTA (Ethylenediaminetetraacetic acid) and its salts have traditionally dominated the shampoo market, their persistent nature and low biodegradability have caused significant concern under European REACH regulations and clean beauty standards. As a result, the cosmetics industry is undergoing a structural transition toward biodegradable alternatives, where Sodium Gluconate (C6H11NaO7) has emerged as the premier green chelant.
Shampoos are primarily composed of anionic and amphoteric surfactants. When used with tap water, these systems encounter divalent cations (specifically Ca2+ and Mg2+). These hard water ions interact with anionic surfactants (such as Sodium Laureth Sulfate or Sodium Cocoyl Isethionate) to form insoluble precipitates, commonly known as soap scum. This precipitate deposits onto the hair shaft, leaving a dull film, stripping natural oils, and significantly reducing the foaming capability of the shampoo.
Sodium Gluconate functions as a polydentate ligand that forms stable, water-soluble coordination complexes with calcium and magnesium ions. At a typical shampoo pH range of 5.5 to 6.5, the carboxyl group (-COO-) of the gluconate molecule is fully deprotonated, coordinating with the metal cations in tandem with the hydroxyl groups (-OH). This prevents the cations from binding to the surfactant head groups, preserving the lather profile, clarifying the hair, and allowing surfactant micelles to perform optimal cleansing.
"Technical Note: Under alkaline conditions, the sequestering power of Sodium Gluconate increases dramatically, making it a highly effective buffer in specialized clarifying shampoos and scalp treatments."
Beyond sequestration, Sodium Gluconate exhibits multi-functional properties that enhance shampoo longevity and skin compatibility. Modern eco-certified shampoos rely on organic acid preservatives (such as sodium benzoate, sorbic acid, or phenoxyethanol). Gram-negative bacteria (e.g., Pseudomonas aeruginosa) possess outer membranes stabilized by calcium and magnesium ions. By sequestering these structural ions, Sodium Gluconate destabilizes the bacterial cell envelope, allowing the primary preservative to penetrate and eliminate microbes more efficiently. This synergy allows formulators to reduce the total concentration of synthetic preservatives, lowering the risk of scalp irritation.
Furthermore, because of its chemical structure rich in hydroxyl groups, Sodium Gluconate acts as a natural humectant. Unlike EDTA, which can leave a dry feel, gluconate binds water molecules to the scalp's stratum corneum, mitigating the harsh drying effects of strong surfactants and improving post-rinse combability.
Analyzing the physicochemical performance and environmental footprint of classic chelating agents compared to Sodium Gluconate.
| Parameter | Sodium Gluconate | Disodium EDTA | Tetrasodium GLDA |
|---|---|---|---|
| Source | Bio-fermentation (Corn/Glucose) | Synthetic (Petrochemical) | Bio-based (L-Glutamic acid) |
| Biodegradability (OECD 301B) | >98% within 28 days (Readily) | <10% (Persistent) | >60% (Readily) |
| Calcium Sequestration Capacity | Excellent at pH > 7; Moderate at pH 5.5 | High across all pH ranges | High across all pH ranges |
| Iron (Fe3+) Binding Capacity | Exceptional (Superior in alkaline range) | High (pH dependent) | Moderate to High |
| Scalp Irritation Index | Non-irritant; Humectant properties | Mild sensitizer in damaged barriers | Very low irritation profile |
| Regulatory Standing | COSMOS Approved / GRAS | Restricted in eco-labels | Eco-label compliant |
A Leading Petrochemical and Specialty Additives Supply Partner Since 2006
Shandong Pulisi Chemical Co., Ltd. was established in 2006 (Stock Code: 307785). The company focuses on petrochemicals, mining chemicals, feed chemicals, and pharmaceutical chemicals. At present, the company has established long-term and stable partnerships with Fortune Global 500 companies such as China National Petroleum Corporation and Saint-Gobain. We always take customer demand as the core orientation and provide tailored solutions to help customers strengthen their market competitiveness.
The company has passed ISO9001:2015 Quality Management System Certification and German BV Certification, and has been awarded multiple honors such as Foreign-Oriented Economic Enterprise, Alibaba Demonstration Base, and Contribution Enterprise. In 2023, the company successfully went public with stock code: 307785.
The company upholds the corporate culture philosophy of "Customer First, Rapid Response; Striving as the Foundation, Efficient Collaboration; Integrity and Uprightness, Agile Adaptation." We focus on providing compliant and high-quality products and supporting services, and are committed to becoming a long-term and stable partner for customers.
Strict Statement: Shandong Pulisi has not established branches outside of Shandong Province. If there is any act of impersonating Shandong Pulisi, our company will reserve the right to pursue legal responsibilities.
Global cosmetics procurement managers face complex regulatory changes regarding synthetic microplastics, palm-oil derivatization, and bio-accumulation. The transition to clean-label shampoos has led to high demand for custom ODM (Original Design Manufacturing) Sodium Gluconate. Procuring departments are no longer searching for generic chemical salts; they require specialty-milled, ultra-low iron, and fast-dissolving grades of Sodium Gluconate that fit directly into automated manufacturing systems.
Our ODM solutions accommodate specific technical demands:
Under current global geopolitical and logistical constraints, chemical supply chain resilience is paramount. Shandong Pulisi Chemical has modernized its production infrastructure through Factory 4.0 smart manufacturing principles. Automatic dosage control, real-time crystallization monitoring, and digitized quality analysis ensure that every batch of cosmetic-grade Sodium Gluconate meets strict specifications.
Logistics efficiency is reinforced by our strategic warehousing network at China's major trade hubs:
We maintain dedicated storage facilities at Qingdao Port and Tianjin Port for rapid sea transport. For transcontinental Eurasian shipments, our integration with Xinjiang border ports (Alashankou and Hhorgos) enables efficient rail and road freight options directly into Central Asia and Eastern Europe. This multimodal capabilities guarantee short lead times, regardless of the target region.
Direct supply of high-grade formates, acetates, and specialty mineral salts manufactured to strict industrial and feed-grade specifications.
Serving key sectors from mining and agriculture to personal care formulations and high-performance building materials.
Chemicals For Textile, Printing & Dyeing & Leather
Agricultural Chemicals, Food And Feed Additives
Chemicals For Construction And Coatings
Chemicals For Mining
Chemicals For Oil Drilling
Disinfectant And Solvent Chemicals
Chemicals For Water Treatment
Plastic Raw Material
Ensuring absolute process transparency, safety certification, and commercial reliability for international procurements.
Exporting to more than 100 countries and regions with professional containerized and bulk cargo shipping arrangements.
More than 20+ years of chemical export experience, maintaining active supply partnerships with over 1,000 global chemical entities.
Fully compliant with ISO Quality management standards. Products undergo routine third-party checks (SGS, K-REACH, FAMI-QS).
Direct factory prices calculated dynamically based on specific customization parameters and raw material markets.
Ample warehouse capacities near Qingdao Port and Tianjin Port guarantee prompt loading and minimal dispatch times.
Prompt communication with technical support teams addressing formulation, regulatory, and shipping documentation issues.
ISO Certificate (Valid to 2028)
FAM-1134 Accreditation
Kosher Certificate
Halal Certificate
ISO 9001 Certificate
Acetic Acid SGS Report
Calcium Formate SGS Report
Formic Acid SGS Report
Since 2006, our team has actively engaged in global chemical trade expos to connect with industry leaders and showcase advanced chemical developments.
Key information regarding sourcing, product personalization, delivery logistics, and transaction terms.
Yes, we provide customizable packaging solutions under ODM terms. Send us your vector logo files and styling details, and our design team will draft the mockups for your approval.
Absolutely. Whether you are a small cosmetic laboratory, startup entrepreneur, or a mid-scale brand looking to pilot test a new formula, we look forward to building a long-term commercial partnership with you.
We always prioritize competitive pricing based on current raw material indexes. Volume discounts are negotiable depending on contract terms, custom formulation requirements, and annual purchase commitment volumes.
Yes, we provide free product samples (up to 1kg) for laboratory valuation and compatibility trials. International shipping/postage costs are paid by the customer.
By maintaining large buffer stocks at our port-adjacent warehouses in Qingdao and Tianjin, we significantly minimize transport lag. Our digital planning system automatically schedules transport runs once quality release reports are signed.
We offer flexible trade payment options, including T/T (Telegraphic Transfer), L/C (Letter of Credit), D/P (Documents Against Payment), and O/A (Open Account) for long-term partners with verified credit scores.
Of course. You are welcome to audit our production facilities in Zibo, Shandong Province (approximately 1.5 hours' drive from Jinan Yaoqiang Airport). Reach out to our sales team to coordinate your visa invitation and schedule.
Submit your inquiry via our web portal or contact your dedicated regional sales executive directly. Specify the required concentration, particle sizes, packaging formats, and delivery terms, and we will guide you through the contracting stages.










Full catalog of organic synthesis intermediates, agricultural chemicals, and specialty raw materials.