In modern industrial synthesis and cosmetic formulation design, Sodium Gluconate (INCI Name: SODIUM GLUCONATE) represents a critical intersection of green chemistry, high-efficiency chelation, and biodegradable performance. As global manufacturing pivots toward strict ESG (Environmental, Social, and Governance) targets, the demand for high-purity, bio-fermented chelating agents has surged exponentially. Shandong Pulisi Chemical Co., Ltd. (Stock Code: 307785) stands at the forefront of this evolution, serving as an elite ODM developer, manufacturer, and global exporter of high-grade Sodium Gluconate.
Under the International Nomenclature of Cosmetic Ingredients (INCI) framework, SODIUM GLUCONATE is officially designated as a chelating and skin-conditioning agent. Structurally, it is the sodium salt of gluconic acid, generated via the enzymatic oxidation of D-glucose. Unlike legacy chelators such as Tetrasodium EDTA (which poses critical concerns regarding marine bioaccumulation and low degradability), Sodium Gluconate is fully biodegradable, non-toxic, and dermatologically benign.
In cosmetic formulations, trace heavy metals (like iron, copper, and manganese) derived from water supplies, botanical extracts, or mineral pigments can catalyze oxidation reactions. This catalysis leads to discoloration, rancidity of natural lipids, and the rapid degradation of active ingredients like Vitamin C and retinol. The chemical structure of Sodium Gluconate enables it to form stable water-soluble ring complexes with these multivalent metal ions across a wide pH range, neutralizing their catalytic properties and extending product shelf-life without irritating sensitive skin types.
By sequestering calcium and magnesium ions required for microbial cell wall integrity, Sodium Gluconate weakens pathogens, allowing organic preservatives to operate at lower concentration thresholds.
Maintains formula equilibrium, preventing phase separation in complex O/W (oil-in-water) emulsions under variable temperature cycles.
Exhibits natural moisturizing properties, serving as a humectant that attracts and binds water molecules to the stratum corneum.
On a macro-industrial scale, Sodium Gluconate is manufactured via two main technological pathways: direct enzymatic conversion and fungal fermentation using Aspergillus niger. The global trade flow of Sodium Gluconate reflects its high versatility. Industrial-grade variants serve as the premier retarder in the construction sector, particularly in high-performance concrete (HPC) formulations where they delay hydration kinetics, allowing for extended workability and transport times in warm climates.
Additionally, its outstanding performance in highly alkaline environments makes it an irreplaceable agent in industrial metal cleaning, textile scour processes, and automated bottle washing systems. As environmental regulations globally restrict phosphate discharges to prevent eutrophication in aquatic ecosystems, Sodium Gluconate has captured substantial market share as the leading replacement builder in institutional detergents and industrial water treatment systems.
To supply high-purity ODM Sodium Gluconate suitable for sensitive cosmetic formulations and specialized technical applications, Shandong Pulisi Chemical utilizes a biological production process. This process reduces reliance on harsh chemical catalysts and maintains an eco-friendly manufacturing cycle.
High-grade corn starch undergoes liquefaction and saccharification to produce a pure D-glucose substrate. This substrate is introduced to specialized microbial cultures under strict oxygenation control.
Gluconic acid produced during fermentation is continuously neutralized with food-grade sodium hydroxide to maintain optimal pH and yield Sodium Gluconate.
The raw broth is processed via multi-stage membrane filtration and activated carbon decolorization to eliminate cellular residue, protein traces, and unwanted by-products.
Controlled evaporative crystallization generates consistent, non-caking crystals, which are dried using fluid-bed technology to ensure stable moisture content.
Our upcoming technical roadmap targets the integration of membrane bioreactors (MBRs) and continuous cell immobilization systems. These upgrades are designed to improve yield efficiency by 15% and lower carbon emissions per metric ton, aligning with global green chemistry initiatives.
The application of Sodium Gluconate varies significantly across regions, driven by local regulatory frameworks and industrial requirements. The table below outlines these specialized applications:
As a publicly traded chemical enterprise in China, Shandong Pulisi Chemical Co., Ltd. (Stock Code: 307785) provides structured supply security to mitigate global logistics and supply chain volatility. Our facility coordinates complex distribution corridors to secure client operations:
To support global supply integration, Pulisi Chemical maintains a comprehensive compliance framework. This structure satisfies international import, safety, and quality standards:
Established in 2006 (Stock Code: 307785), Shandong Pulisi Chemical Co., Ltd. has grown into a leading modern enterprise focusing on petrochemicals, mining chemicals, feed chemicals, and pharmaceutical chemicals. Over nearly two decades of intensive development, we have established long-term and stable partnerships with Fortune Global 500 companies such as China National Petroleum Corporation (CNPC) and Saint-Gobain.
The company has passed ISO9001:2015 Quality Management System Certification and German BV Certification. We have been awarded multiple honors such as Foreign-Oriented Economic Enterprise, Alibaba Demonstration Base, and Contribution Enterprise. In 2023, the company successfully went public with stock code: 307785.
We have established mature warehousing and distribution systems at key logistics hubs, including Qingdao Port, Tianjin Port, and Xinjiang border ports (Alashankou, Khorgos). This network allows us to provide flexible supply solutions tailored to customer needs, ensuring timely order delivery. No matter where you are located, Shandong Pulisi Chemical supports your business development with professional service and efficient response capabilities.








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Exporting to more than 100 countries and regions with fully localized logistic support.
More than 20+ years of export experience, maintaining cooperative relations with more than 1,000 global companies.
ISO Certification, SGS certification, K-REACH Registration compliance, and FAMI-QS Certification.
We always provide reasonable prices based on customization and design requirements.
We have large warehouses in the port which can realize fast transportation and loading.
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