Calcium Hydrogen Phosphate Anhydrous (commonly referred to as Dibasic Calcium Phosphate Anhydrous or DCP Anhydrous, CAS No. 7757-93-9) serves as a corner-stone mineral nutrient, excipient, and structural binder. Unlike its dihydrate counterpart (DCP Dihydrate, CaHPO₄·2H₂O), the anhydrous form possesses high thermal stability and resistance to dehydration-induced chemical degradation. This makes it a preferred selection for advanced solid dosage systems, mineral supplements, and industrial formulations requiring critical water-activity levels.
From an industrial perspective, the absence of crystalline water translates into high compatibility with moisture-sensitive active ingredients, including vitamins, antibiotics, and highly reactive active pharmaceutical ingredients (APIs). Shandong Pulisi Chemical Co., Ltd. supplies premium-grade Calcium Hydrogen Phosphate Anhydrous designed to maintain optimal flowability, high compaction profiles, and precise mineral bio-accessibility.
Chemical Properties: Empirically denoted as CaHPO₄, it yields a molecular weight of 136.06 g/mol. It exhibits a high phosphorus content (approx. 22.8%) and calcium content (approx. 29.5%), presenting as an odorless, white, crystalline powder that is practically insoluble in water and ethanol, yet highly soluble in dilute acidic environments.
Understanding the thermodynamic behavior and engineering differences between Dibasic Calcium Phosphate Anhydrous and Dihydrate forms is vital for formulation optimization. The table below details why procurement managers specify the anhydrous variation for advanced product lines:
| Parameters | Calcium Hydrogen Phosphate Anhydrous (CaHPO₄) | Calcium Hydrogen Phosphate Dihydrate (CaHPO₄ · 2H₂O) | Formulation Implications |
|---|---|---|---|
| Crystalline Water Content | 0% (Loss on Drying / Ignition < 2%) | ~20.9% (Structural Water Bound in Crystal Matrix) | Anhydrous prevents degradation of water-sensitive molecules. |
| Thermal Stability Limit | Stable up to >200°C | Begins losing crystalline water at ~70°C–80°C | Anhydrous is ideal for high-temperature processing/extrusion. |
| Abrasiveness Profile | Higher abrasive value (Mohs scale 3.5) | Lower abrasive value (Mohs scale 2.5) | Anhydrous functions as a stable polishing agent in dentifrices. |
| Compaction Properties | Primarily deforms via brittle fracture under load | Deforms plastically under moderate pressure | Anhydrous delivers robust tablet hardness at high pressures. |
| Bulk Density | Typically 0.85 – 1.05 g/cm³ | Typically 0.65 – 0.85 g/cm³ | Allows smaller capsule sizes and space-efficient packaging. |
The global demand for Calcium Hydrogen Phosphate Anhydrous spans pharmaceutical excipients, premium animal nutrition, and infant food fortification. As regulatory authorities raise the bar for heavy metal thresholds (specifically Lead, Arsenic, Cadmium, and Mercury), manufacturers must show strict control over sourcing and processing pathways. Sourcing from validated Chinese manufacturers like Shandong Pulisi Chemical provides international buyers with guaranteed batch traceability.
For drug manufacturers, DCP Anhydrous serves as an insoluble binder-filler in direct compression tableting. Ensuring compliance with the USP-NF, European Pharmacopoeia (Ph. Eur.), and British Pharmacopoeia (BP) is non-negotiable. Our production lines feature inline particle-size distribution (PSD) laser monitoring to prevent segregation risks in final dry-blend steps.
In food fortification, DCP Anhydrous operates as an emulsifier, stabilizer, and nutrient supplement. Controlling fluoride impurities is critical here, as infant formulations demand fluoride levels below 50 ppm. Pulisi utilizes multi-stage recrystallization steps to consistently hit ultra-low fluoride yields.
For high-yield animal feed, bioavailability of phosphorus is the main metric. While generic feed phosphates present varying solubility profiles, our feed-grade Calcium Hydrogen Phosphate achieves high biological digestibility in monogastric species, translating to improved feed conversion ratios (FCR).
Established in 2006 (Stock Code: 307785), Shandong Pulisi Chemical Co., Ltd. has grown into a leading industrial supply engine in China. We focus on petrochemicals, mining chemicals, feed chemicals, and pharmaceutical chemicals. Currently, the company has established long-term and stable partnerships with Fortune Global 500 companies such as China National Petroleum Corporation and Saint-Gobain. We take customer demand as our core focus, providing tailored chemical solutions to strengthen our customers' market competitiveness.
The company has passed ISO9001:2015 Quality Management System Certification and German BV Certification. We have been awarded multiple honors, including "Foreign-Oriented Economic Enterprise", "Alibaba Demonstration Base", and "Contribution Enterprise". In 2023, the company successfully listed on the stock market with stock code: 307785.
To guarantee reliable global supply lines, we operate mature warehousing and distribution networks at key logistics hubs including Qingdao Port, Tianjin Port, and Xinjiang border ports (Alashankou, Khorgos). No matter where you operate, Shandong Pulisi ensures business continuity through rapid response and verified compliance.
Our chemical operations are audited, verified, and certified by leading international third-party bodies, confirming our status as a reliable and transparent chemical producer in China.
We maintain a rigorous quality assurance framework validated by multiple international standards. Our chemical portfolios are certified under global food safety, feed safety, and quality management systems.
Since 2006, Shandong Pulisi Chemical has committed to establishing active partnerships worldwide. We participate in major trade events to connect with industry leaders and align our offerings with the evolving requirements of our global clients.
The manufacturing process of Calcium Hydrogen Phosphate Anhydrous is designed to limit chemical impurities and prevent the formation of hydrated phases. Production occurs via one of two primary pathways:
Thermal phosphoric acid (produced from elemental phosphorus) is reacted with ultra-filtered calcium hydroxide slurry. Because the starting acid has minimal heavy metal contamination, this pathway is favored for pharmaceutical excipients requiring low levels of Lead (Pb) and Arsenic (As). Reaction temperatures are held above 85°C to suppress the crystallization of dihydrate phases, promoting direct precipitation of the anhydrous monoclinic form.
Using wet-process phosphoric acid, this method involves multi-stage extraction and desulfurization to remove trace sulfates, fluorides, and iron oxides. The purified stream undergoes precipitation under controlled pH ranges. It serves as an efficient route for food-grade and high-grade feed additives, striking an optimal balance between bioavailability and production economics.
Quality Control Directive: Every batch produced by Shandong Pulisi undergoes X-ray Diffraction (XRD) analysis to confirm the absence of the dicalcium phosphate dihydrate crystalline phase. This ensures that customers receive pure anhydrous product that will not release volatile moisture during high-energy compaction or high-temperature drying steps.
Our high-purity chemical range supports diverse applications across key industries, backed by our technical consulting and compliance expertise.
Textile, Printing, Dyeing & Leather
Agricultural, Food & Feed Additives
Construction & Coatings
Mining Chemicals
Oil Drilling Chemicals
Disinfectant & Solvent Chemicals
Water Treatment Chemicals
Plastic Raw Materials
We provide specialized formulations under strict quality control to support our global clients' performance requirements.
We combine manufacturing capacity, global logistics, and compliance support to deliver competitive sourcing solutions for our clients.
Exporting to more than 100 countries and regions with verified logistics pathways.
Over 20+ years of export experience, maintaining active collaborations with over 1,000 global partners.
ISO Certification, SGS reports, K-REACH pre-registration, and FAMI-QS certification.
Large warehouses at key ports to streamline dispatch and reduce transit times.
We operate dedicated consolidation warehouses near the major logistics centers of Qingdao Port and Tianjin Port. This proximity allows for rapid cargo loading and custom clearance. For land-based routes to Central Asia and Europe, our dedicated logistics links via the Alashankou and Khorgos border crossings in Xinjiang enable secure, multi-modal containerized transport.
Our standard export configuration for Calcium Hydrogen Phosphate Anhydrous features double-layer polyethylene inner bags within multi-ply paper bags (25kg net weight), palletized and shrink-wrapped. We also offer 1,000kg bulk supersacks with custom discharge spouts designed to fit standard industrial feed hoppers.
As a global chemical supplier, Shandong Pulisi complies with localized regulatory requirements across major regions:
We maintain active partnerships with leading domestic and multinational corporations, coordinating quality standards and logistics to support major projects.
The phosphate chemical industry is evolving under global decarbonization directives and resource efficiency targets. As a listed enterprise, Shandong Pulisi adapts to these trends by implementing clean production technologies:
We are integrating closed-loop chemical reclamation loops that capture heat from the exothermic neutralization reaction between phosphoric acid and lime. This reduced carbon footprint aligns with our customers' Scope 3 emission reduction goals.
The tablet manufacturing industry is moving toward direct compression (DC) to streamline operations. Pulisi is designing specific grades of Calcium Hydrogen Phosphate Anhydrous with modified particle shape factors (spherical aggregates) to optimize powder flowability and stability during high-speed compression cycles.
Integrating artificial-intelligence optical inspection and automated grain analysis on our crystallization units guarantees consistent particle size distributions, reducing batch-to-batch variation for global buyers.
Review answers to standard technical, commercial, and logistical questions. If you require additional detail or a formal quotation, please reach out directly.
Yes, we offer custom packaging services. You can send us your logo design and branding specifications, and we will apply your marks to our multi-ply paper bags or big bags in compliance with export labeling regulations.
Yes. Whether you are a small retailer or a scaling entrepreneur, we support your development. We look forward to building a long-term commercial partnership by starting with manageable trial quantities.
We prioritize our customers' commercial competitiveness. Prices vary based on grade specifications, order volume, and packaging configurations. We negotiate under clear business conditions to ensure you receive a competitive factory-direct quote.
Yes, we provide free pre-shipment samples for quality testing. Contact our sales department with your specifications and carrier details to arrange delivery.
We coordinate our production schedules with dedicated storage facilities at Qingdao Port and Tianjin Port. This setup helps avoid typical supply chain delays and ensures reliable shipment dispatch.
We accept a variety of standard payment terms including T/T (Telegraphic Transfer), L/C (Letter of Credit) at sight, D/P (Documents Against Payment), and O/A (Open Account) for established clients. Third-party payments can be arranged subject to compliance review.
You are welcome to visit our headquarters and production facilities in Zibo, Shandong Province, China. The plant is approximately a 1.5-hour drive from Jinan Yaoqiang International Airport.
You can send an inquiry directly to our sales representatives. Our team will guide you through the process, from detailing chemical specifications to arranging logistics and dispatch.
Keep the product in a cool, dry, well-ventilated warehouse, away from incompatible materials. Store it off the floor on pallets to avoid moisture exposure from ground condensation. Keep the bags sealed until use.
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