Global Standard Bulk Chemicals and Specialized Raw Materials
In analytical chemistry, pharmaceutical formulation, and high-performance liquid chromatography (HPLC), the solvent utilized is not merely a carrier medium but an integral variable affecting final outcomes. Acetonitrile Ph (focusing specifically on pH-controlled/buffered chromatographic and pharmacopoeia grades) represents a critical industrial chemical requiring meticulous production and export management. Acetonitrile ($CH_3CN$) features a low viscosity, high elution strength, and minimal UV cutoff wavelength, making it the globally preferred choice for analytical labs and manufacturing units.
The suffix "Ph" highlights two major industry requirements: First, alignment with international pharmacopoeias (USP, EP, JP) for the synthesis and purification of active pharmaceutical ingredients (APIs). Second, specific control over pH stability, volatile acidity, and alkalinity to prevent chemical decomposition of complex organic chains during separation processes. Without precise acid-base stabilization, trace acidic or basic impurities in Acetonitrile catalyze degradation, ruining high-value compounds like peptides and oligonucleotide chains.
To ensure total clarity for global procurement departments, our manufacturing processes maintain strict operational boundaries:
| Parameters Assayed | Standard Grade | HPLC / Chromatographic Grade | Pharma (Ph) / Oligo Synthesis Grade |
|---|---|---|---|
| Assay (GC, on anhydrous basis) | ≥ 99.0% | ≥ 99.9% | ≥ 99.99% |
| Water Content (Karl Fischer) | ≤ 0.1% (1000 ppm) | ≤ 0.01% (100 ppm) | ≤ 0.001% (10 ppm) |
| Acidity (as CH3COOH) / pH Buffer | ≤ 0.05% | ≤ 0.001% | ≤ 0.0005% (pH stabilized) |
| UV Transmittance (at 200 nm) | N/A | ≥ 90% | ≥ 97% |
| Residue after Evaporation | ≤ 0.005% | ≤ 0.0005% | ≤ 0.0001% |
Ensuring ultra-purification and zero contamination from feedstock to delivery
High-grade acrylonitrile byproduct streams are continuously collected under strict process conditions, filtering heavy components and volatile organics before initial distillation stages.
Chemical oxidation techniques remove stubborn unsaturated organic impurities and amine contaminants, which otherwise interfere with critical UV transmittance levels.
Water content is reduced from percentages to single-digit parts per million (ppm) via chemical entrainers coupled with fractional columns working under precise pressure curves.
The final ultra-pure Acetonitrile is stored under high-purity nitrogen padding in stainless steel containers to prevent atmospheric moisture ingress and oxidation prior to global shipping.
Shandong Pulisi Chemical Co., Ltd. (Stock Code: 307785)
Shandong Pulisi Chemical Co., Ltd. was established in 2006 (Stock Code: 307785). The company focuses on petrochemicals, mining chemicals, feed chemicals, and pharmaceutical chemicals. At present, the company has established long-term and stable partnerships with Fortune Global 500 companies such as China National Petroleum Corporation and Saint-Gobain. We always take customer demand as the core orientation and provide tailored solutions to help customers strengthen their market competitiveness.
The company has passed ISO9001:2015 Quality Management System Certification and German BV Certification, and has been awarded multiple honors such as Foreign-Oriented Economic Enterprise, Alibaba Demonstration Base, and Contribution Enterprise. In 2023, the company successfully went public with stock code: 307785.
Meanwhile, the company has established mature warehousing and distribution systems at key logistics hubs, including Qingdao Port, Tianjin Port, and Xinjiang border ports (Alashankou, Khorgos). We are able to provide flexible supply solutions according to customer needs to ensure timely order delivery. No matter where customers are located, Shandong Pulisi Chemical will safeguard their business development with professional service systems and efficient response capabilities.
We always adhere to the mission of "creating value for customers and making their products better," based on reputation and guaranteed by service. We look forward to strengthening cooperation with partners to create a future together!
Strict Statement: Shandong Pulisi has not established branches outside of Shandong Province. If there is any act of impersonating Shandong Pulisi, our company will reserve the right to pursue legal responsibilities.
Rigorous quality controls conforming to strict global regulatory guidelines
Addressing the complex supply requirements of top-tier pharmaceutical and analytical manufacturers
In peptide and oligonucleotide synthesis (e.g., active ingredients for GLP-1 receptor agonists, monoclonal antibodies, gene therapy vectors), Acetonitrile acts as the main chemical vehicle during critical solid-phase synthesis. Our OEM solutions offer customizable ultra-low water grades (<10 ppm) to ensure critical amino acids couple with maximum chemical efficiency. Trace moisture causes premature termination of coupling reactions, leading to sub-optimal purity and extremely costly batch losses for biopharma producers.
Analytical testing facilities worldwide require consistent solvent qualities to ensure zero shift in baseline signals. Shandong Pulisi Chemical Co., Ltd. processes its OEM Acetonitrile products with micro-purification units that remove heavy metals, halogenated organics, and free halogens. This guarantees that during gradient elution processes, HPLC baseline noise is kept to absolute minimums, protecting expensive analytical columns from premature degradation and mechanical fouling.
We recognize that different industrial clients operate unique warehouse layouts and safety regimes. We provide various secure packaging formats designed for toxic and flammable solvent classifications:
Your Reliable Industrial Chemical Partner
Exporting to more than 100 countries and regions worldwide with stable maritime routing and customs operations.
More than 20+ years of export experience, maintaining active cooperative relations with more than 1,000 global enterprises.
ISO 9001 Certification, German BV Certification, K-REACH registrations, and comprehensive FAMI-QS guidelines compliance.
We consistently provide highly competitive, direct factory pricing based on custom specifications and regional volume needs.
Large warehouses at key logistics hubs including Qingdao Port, Tianjin Port, and Xinjiang border stations (Alashankou/Khorgos) ensure rapid transit.
Our responsive sales team provides multilingual scientific support, tracking batches from synthesis to your dock.
Catering to a highly diversified range of downstream chemical processes
Explore our core organic syntheses and industrial grade chemical outputs
Connecting with partners global industry players face-to-face since 2006
Cooperating with Fortune Global 500 companies and premier distribution systems
Commercial Queries & Technical Clarifications regarding Acetonitrile Ph & OEM Shipments
Advanced Synthetics and Bulk Technical Grade Offerings
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